The Sun Arena at Time Square Casino, Menlyn, will be the place to be when the "Evening Of Love" kicks off on Wednesday night.
The event is all about celebrating love, and will be hosted by Somizi Mhlongo.
The crème de la crème of South African Afro-pop is set to perform.
The line-up includes Kelly Khumalo, Vusi Nova, Thami Shobede, La Sauce, Ntando, Samthing Soweto and Bekezela.
Speaking to HuffPost, both Thami Shobede and La Sauce said they could not contain their excitement ahead of the event.
"People can look forward to hearing my hit song, "I Do" as well as a whole lot of others," La Sauce said.
Shobede said he was gearing up for the performance of his life.
"I plan to give people a performance they will never forget. It's going to be a great night of love and music," he told HuffPost.
Here's a teaser from last year's instalment.
The show starts at 7pm and tickets range from R250 to R1,500 at Computicket.