"The Big Bang Theory" star told host Jimmy Fallon that while he was auditioning for graduate drama schools in the late Nineties, he used the pop star's "Baby One More Time" video as inspiration when he was "trying to get focused".
The image of Spears dancing in the hallway in "that Catholic school girl uniform" did the trick, he said.
"Something about that song, and especially that video, really worked for me," Parsons said. "Obviously not in a sexual way ― I'm a good gay! But there was something inspirational."
Parsons noted that he got into school "and I eventually got a career. So I give a lot of credit for my acting career to Britney".